Le knockdown de Fus inhibe l’effet profibrogène des fibroblastes cardiaques induits par l’angiotensine II en ciblant Pax3, régulant ainsi la voie TGF- / 1 / Smad
The Angiotensin II/transforming growth factor-β1 (AngII/TGF-β1) signal axis is an important regulatory pathway for atrial fibrosis, which can contribute to atrial fibrillation (AF). Fused in sarcoma (FUS) was recently found to regulate cardiac diseases. This study aimed to investigate whether FUS could regulate AngII induced fibrosis and uncover the possible mechanisms. The expression of FUS in AF patients and AngII-induced cardiac fibroblasts was measured by RT-qPCR and western blot assays. Fus was silenced in cells using short hairpin RNA (shRNA), then cell proliferation, migration, collagen synthesis and TGF-β1/Smad signaling were detected by CCK-8, wound healing and western blot assays, respectively. The possible target for Fus was predicted by searching Starbase database and verified by RNA-binding protein immunoprecipitation (RIP) and RNA pull down.
Cells were overexpressed with Pax3 in the presence of Fus silence and AngII stimulation, then the above cellular processes were further evaluated. Results showed that FUS was upregulated in AF patients and AngII-induced cardiac fibroblasts. Fus knockdown inhibited AngII-enhanced cell proliferation, migration, collagen synthesis and TGF-β1/Smad signaling activation. Furthermore, Fus functions as an RNA-binding protein to bind to Pax3 mRNA and positively regulate its expression. Further studies demonstrated that Pax3 overexpression canceled the above effects of Fus knockdown on cell proliferation, migration, collagen synthesis, and TGF-β1/Smad signaling activation in AngII-induced cells. In conclusion, Fus could target Pax3 to increase the pro-fibrotic effect of AngII in cardiac fibroblasts via activating TGF-β1/Smad signaling. Knockdown of Fus/Pax3 axis may provide a potential therapy for relieving AF.

Immortalized Human Uterine Fibroblasts |
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TIMP-2, human fibroblasts |
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7788-5 | Biovision | each | EUR 405.6 |
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Immortalized Human Gingival Fibroblasts- hTERT |
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Immortalized Human Mammary Fibroblasts (HMF3S) |
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Immortalized Human Neonatal Fibroblasts - hTERT |
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Immortalized Rat Embryonic Fibroblasts (18IM) |
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Immortalized Human Pulmonary Fibroblasts Cells |
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Immortalized Human Corneal Fibroblasts (IHCF) |
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T0578 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Diploid Fibroblasts - hTERT |
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T1013 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts |
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2-82007 | CHI Scientific | 1 Kit | Ask for price |
Mouse Brain PrimaCell1: Normal Brain Fibroblasts |
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2-82010 | CHI Scientific | 1 Kit | Ask for price |
Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts |
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2-82024 | CHI Scientific | 1 Kit | Ask for price |
Mouse Eye PrimaCell3: Normal Corneal Fibroblasts |
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2-82039 | CHI Scientific | 1 Kit | Ask for price |
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2-82047 | CHI Scientific | 1 Kit | Ask for price |
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2-82065 | CHI Scientific | 1 Kit | Ask for price |
Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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2-82073 | CHI Scientific | 1 Kit | Ask for price |
Rat Bladder PrimaCell2: Normal Bladder Fibroblasts |
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2-82507 | CHI Scientific | 1 Kit | Ask for price |
Rat Brain PrimaCell1: Normal Brain Fibroblasts |
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2-82511 | CHI Scientific | 1 Kit | Ask for price |
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2-82540 | CHI Scientific | 1 Kit | Ask for price |
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DMABT-49595MH | Creative Diagnostics | 25 TEST | EUR 514.8 |
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9-80279 | CHI Scientific | 1 x 100 ml | Ask for price |
Lung Dissociation System 6 (Fibroblasts & Type II), Mouse and Rat |
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4-20316 | CHI Scientific | ea | Ask for price |
Human Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts |
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9-80273 | CHI Scientific | 1 x 100 ml | Ask for price |
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4-20231 | CHI Scientific | ea | Ask for price |
Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Medium |
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9-25003 | CHI Scientific | 5 x 100 ml | Ask for price |
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9-32003 | CHI Scientific | 5 x 100 ml | Ask for price |
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Rat Ariway Tissue Preparation Buffer 3: Normal Bronchial and and Tracheal Fibroblasts |
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9-80210 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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9-47030 | CHI Scientific | 1 Set | Ask for price |
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ASAP1 antibody Antibody |
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DF8746 | Affbiotech | 200ul | EUR 420 |
CD11b Antibody Antibody |
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ABD2911 | Lifescience Market | 100 ug | EUR 525.6 |
anti- Antibody^Polyclonal antibody control antibody |
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LSMab09882 | Lifescience Market | 100 ug | EUR 525.6 |
ARHGDIA Antibody / RHOGDI Antibody |
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F54788-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
ARHGDIA Antibody / RHOGDI Antibody |
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F54788-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
Antibody |
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A1360-500 | Biovision | each | Ask for price |
Ly1 Antibody Reactive (LYAR) Antibody |
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20-abx123734 | Abbexa |
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Anti-Glycolipid Antibody (AGA) Antibody |
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20-abx004855 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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20-abx014333 | Abbexa |
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L’acide salvianolique B inhibe la différenciation des myofibroblastes et l’accumulation de matrice extracellulaire dans les fibroblastes polypes nasaux via la voie de signalisation TGF-sign1
In the process of nasal tissue remodeling, nasal fibroblasts serve an important role via myofibroblast differentiation and the production of extracellular matrix (ECM). Nasal fibroblast abnormalities can lead to conditions such as chronic rhinosinusitis. Salvianolic acid B (Sal B), a water-soluble active pharmaceutical compound extract from the root of the traditional Chinese medicine Salvia miltiorrhiza, displays antioxidative, antiproliferative and antifibrosis properties. The present study aimed to investigate the mechanism underlying the effects of Sal B on nasal polyp fibroblast (NPF) myofibroblast differentiation and ECM accumulation. Primary NPFs were obtained from nasal polyps of patients with chronic sinusitis. The proliferative and cytotoxic effects of Sal B on NPFs were evaluated by performing the Cell Counting Kit-8 assay.
The Transwell assay was conducted to assess cell migration. α-smooth muscle actin (α-SMA), TGF-β1 receptor (TβR)-I, TβR-II, Smad2/3 mRNA and protein expression levels and (p)-Smad2/3 phosphorylation levels were measured via reverse transcription-quantitative PCR and western blotting, respectively. Type III collagen and fibronectin levels were analyzed by ELISA. The results indicated that Sal B significantly downregulated TGF-β1-induced α-SMA, fibronectin and collagen III expression levels in NPFs. Similarly, Sal B significantly decreased TGF-β1-induced TβR-I, TβR-II, p-Smad2/3, MMP-2 and MMP-9 mRNA and protein expression levels in NPFs. Furthermore, Sal B significantly decreased TGF-β1-induced NPF migration. Therefore, the present study indicated that Sal B inhibited myofibroblast differentiation and ECM accumulation in nasal fibroblasts, suggesting that Sal B may inhibit nasal polyp formation via certain mechanisms.
E2F2 stimule l’expression de CCR4 et active les cellules de type fibroblaste synovial dans la polyarthrite rhumatoïde
Aim of the study: E2F transcription factor 2 (E2F2) has increased expression in synovial tissues of rheumatoid arthritis (RA) and stimulates interleukin (IL)-1 α and IL-β production in cultured RA synovial fibroblast-like cells (RASF), which supports the importance of E2F2 in RA pathogenesis. This study investigated the effect and mechanism of E2F2 in RA.
Material and methods: Cultured RASF were transfected with anti-E2F2 siRNA, and the expression profile was analyzed with an inflammatory response and autoimmunity PCR array loaded with 84-relative genes to explore the pathogenic pathway of E2F2. Apoptosis, migration and tube-like structure formation in the RASF with transfection of anti-E2F2 siRNA or E2F2-expressing plasmids were examined using flow cytometry, transwell assays and Matrigel assays, respectively.
Results: Significantly decreased expression of chemokine receptor 4 (CCR4) was detected in RASF with inhibited E2F2 expression, and the CCR4 expression was increased in RASF with transfection of E2F2-expressing plasmids. Silencing E2F2 expression stimulated apoptosis, but retarded migration and tube-like structure formation in RASF. The opposite observation was obtained in RASF with E2F2 overexpression.
Conclusions: High E2F2 expression decreases apoptosis and increases migration and tube-like structure ability in RASF and might perform this role by up-regulating CCR4 expression, which ultimately contributes to the disease progression of RA synovial tissues.
Taux de sécrétion et composition protéique des vésicules extracellulaires libérées par les fibroblastes associés au cancer après irradiation
Reciprocal communication between the malignant and non-malignant cellular elements in tumors is essential for cancer sustainability and plays an important role in the response of cancers to treatments. Some of this cellular crosstalk takes place via secretion of vesicles that are actively released into the extracellular space by most cell types in tumors. Recent studies have demonstrated radiation-induced changes in the secretion rate and composition of extracellular vesicles (EVs), with impact on radiation-related cellular communication.
However, little is known about the effects of different radiation regimens on the release of EVs by cells of the tumor microenvironment. In this study, we provide a comprehensive molecular characterization of EVs released by cultured primary lung tumor fibroblasts. We explore the quantitative and morphological changes triggered by ionizing radiation (IR), delivered as a single dose of 18 Gy or three consecutive daily medium-doses of 6 Gy. Cancer-associated fibroblasts (CAFs) secrete EVs with sizes ranging from 80 to 200 nm, expressing some of the classical exosome markers. Exposing CAFs to a single-high radiation dose (1 × 18 Gy) or fractionated medium-dose did not alter the release of CAF-EVs.
The protein composition of CAF-EVs was analyzed by LC-MS/MS proteomics and revealed that CAF-EVs are enriched with heat shock proteins, integrins, tetraspanins, proteinases, collagens, growth factors and an array of molecules involved in the regulation of cell migration and the immune system. Quantitative proteomic analyses revealed minor changes in the protein composition of CAF-EVs after radiation exposure. Taken together, this study presents original data on lung tumor CAF-EV composition and reveals that release and protein cargo of CAF-EVs are largely unaltered after exposing CAFs to IR.
Human Cancer PrimaCell7: Esophageal Fibroblasts |
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2-96030 | CHI Scientific | 1 Kit | Ask for price |
Immortalized Human Gingival Fibroblasts- hTERT |
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T0026 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Mammary Fibroblasts (HMF3A) |
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T0153 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Mammary Fibroblasts (HMF3S) |
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T0154 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Neonatal Fibroblasts - hTERT |
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T0344 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Rat Embryonic Fibroblasts (18IM) |
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T0354 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Pulmonary Fibroblasts Cells |
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T0490 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Corneal Fibroblasts (IHCF) |
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T0578 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Diploid Fibroblasts - hTERT |
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T1013 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts |
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2-82007 | CHI Scientific | 1 Kit | Ask for price |
Mouse Brain PrimaCell1: Normal Brain Fibroblasts |
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2-82010 | CHI Scientific | 1 Kit | Ask for price |
Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts |
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2-82024 | CHI Scientific | 1 Kit | Ask for price |
Mouse Eye PrimaCell3: Normal Corneal Fibroblasts |
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2-82039 | CHI Scientific | 1 Kit | Ask for price |
Mouse Heart PrimaCell3: Normal Heart Fibroblasts |
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2-82047 | CHI Scientific | 1 Kit | Ask for price |
Mouse Lung PrimaCell2: Normal Lung Fibroblasts |
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2-82065 | CHI Scientific | 1 Kit | Ask for price |
Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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2-82073 | CHI Scientific | 1 Kit | Ask for price |
Rat Bladder PrimaCell2: Normal Bladder Fibroblasts |
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2-82507 | CHI Scientific | 1 Kit | Ask for price |
Rat Brain PrimaCell1: Normal Brain Fibroblasts |
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2-82511 | CHI Scientific | 1 Kit | Ask for price |
Rat Cervix PrimaCell2: Normal Cervical Fibroblasts |
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2-82525 | CHI Scientific | 1 Kit | Ask for price |
Rat Eye PrimaCell3: Normal Corneal Fibroblasts |
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2-82540 | CHI Scientific | 1 Kit | Ask for price |
Rat Heart PrimaCell3: Normal Heart Fibroblasts |
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2-82548 | CHI Scientific | 1 Kit | Ask for price |
Rat Lung PrimaCell1: Normal Lung Fibroblasts |
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2-82564 | CHI Scientific | 1 Kit | Ask for price |
Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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2-82572 | CHI Scientific | 1 Kit | Ask for price |
Human Bladder PrimaCell2: Normal Bladder Fibroblasts |
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2-96008 | CHI Scientific | 1 Kit | Ask for price |
Human Brain PrimaCell1: Normal Brain Fibroblasts |
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2-96013 | CHI Scientific | 1 Kit | Ask for price |
Human Cervix PrimaCell2: Normal Cervical Fibroblasts |
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2-96045 | CHI Scientific | 1 Kit | Ask for price |
Human Eye PrimaCell3: Normal Corneal Fibroblasts |
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2-96059 | CHI Scientific | 1 Kit | Ask for price |
Human Heart PrimaCell3: Normal Heart Fibroblasts |
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2-96068 | CHI Scientific | 1 Kit | Ask for price |
Human Lung PrimaCell1: Normal Lung Fibroblasts |
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2-96081 | CHI Scientific | 1 Kit | Ask for price |
Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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2-96089 | CHI Scientific | 1 Kit | Ask for price |
Human Mouth PrimaCell: Normal Periodontal Fibroblasts |
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2-96090 | CHI Scientific | 1 Kit | Ask for price |
Human Skin PrimaCell: Normal Skin Fibroblasts |
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2-96103 | CHI Scientific | 1 Kit | Ask for price |
Mouse Anti Human Fibroblasts/Epithelial Cells Monoclonal Antibody,RPE |
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DMABT-49595MH | Creative Diagnostics | 25 TEST | EUR 514.8 |
Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts |
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2-82031 | CHI Scientific | 1 Kit | Ask for price |
Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts |
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2-82067 | CHI Scientific | 1 Kit | Ask for price |
Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts |
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2-82532 | CHI Scientific | 1 Kit | Ask for price |
Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts |
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2-82566 | CHI Scientific | 1 Kit | Ask for price |
Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts |
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2-96051 | CHI Scientific | 1 Kit | Ask for price |
Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts |
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2-96083 | CHI Scientific | 1 Kit | Ask for price |
Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Medium |
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9-46030 | CHI Scientific | 5 x 100 ml | Ask for price |
Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-Myc |
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T0253 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-SV40 |
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T0257 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-Ras |
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T0258 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Bcl-x Mouse Embryonic Fibroblasts - SV40T |
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T0749 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Kidney Dissociation System 5 (Fibroblasts), Mouse and Rat |
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4-29295 | CHI Scientific | ea | Ask for price |
Rat Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium |
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9-25007 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium |
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9-25011 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium |
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9-25025 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium |
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9-25040 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium |
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9-25048 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Lung PrimaCell1: Normal Lung Fibroblasts Growth Medium |
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9-25064 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium |
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9-25072 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium |
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9-32007 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium |
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9-32010 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium |
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9-32024 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium |
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9-32039 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium |
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9-32047 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Lung PrimaCell2: Normal Lung Fibroblasts Growth Medium |
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9-32065 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium |
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9-32073 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium |
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9-46008 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium |
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9-46013 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium |
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9-46045 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium |
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9-46059 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium |
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9-46068 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Lung PrimaCell1: Normal Lung Fibroblasts Growth Medium |
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9-46081 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium |
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9-46089 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Mouth PrimaCell: Normal Periodontal Fibroblasts Growth Medium |
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9-46090 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Skin PrimaCell: Normal Skin Fibroblasts Growth Medium |
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9-46103 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Cancer Tissue Preparation Buffer 7: Esophageal Fibroblasts |
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9-80030 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Mouth Tissue Preparation Buffer: Normal Periodontal Fibroblasts |
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9-80090 | CHI Scientific | 1 x 100 ml | Ask for price |
Heart Dissociation System 11 (Cardiomycytes,Fibroblasts), Mouse and Rat |
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4-20281 | CHI Scientific | ea | Ask for price |
Mouse Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts |
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2-82003 | CHI Scientific | 1 Kit | Ask for price |
Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts |
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2-82503 | CHI Scientific | 1 Kit | Ask for price |
Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts |
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2-96004 | CHI Scientific | 1 Kit | Ask for price |
Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium |
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9-25032 | CHI Scientific | 5 x 100 ml | Ask for price |
Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Medium |
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9-25066 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium |
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9-32031 | CHI Scientific | 5 x 100 ml | Ask for price |
Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts Growth Medium |
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9-32067 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium |
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9-46051 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Medium |
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9-46083 | CHI Scientific | 5 x 100 ml | Ask for price |
Human Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts |
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9-80008 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts |
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9-80013 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts |
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9-80045 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts |
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9-80059 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts |
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9-80068 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Lung Tissue Preparation Buffer 1: Normal Lung Fibroblasts |
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9-80081 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts |
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9-80089 | CHI Scientific | 1 x 100 ml | Ask for price |
Human Skin Tissue Preparation Buffer 3: Normal Skin Fibroblasts |
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9-80103 | CHI Scientific | 1 x 100 ml | Ask for price |
Mouse Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts |
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9-80121 | CHI Scientific | 1 x 100 ml | Ask for price |
Mouse Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts |
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9-80124 | CHI Scientific | 1 x 100 ml | Ask for price |