La glycation par le glyoxal entraîne de profonds changements dans le comportement des fibroblastes dermiques
Introduction: Diabetes is a worldwide well being downside that’s related to extreme issues. Superior Glycation Finish merchandise (AGEs) akin to Nε-(carboxymethyl)lysine, which end result from power hyperglycemia, accumulate within the pores and skin of sufferers with diabetes. The impact of AGEs on fibroblast performance and their affect on wound therapeutic are nonetheless poorly understood.
Analysis design and strategies: To analyze this, we handled cultured human fibroblasts with 0.6 mM glyoxal to induce acute glycation. The conduct of fibroblasts was analyzed by time-lapse monolayer wounding therapeutic assay, seahorse know-how and atomic drive microscopy. Manufacturing of extracellular matrix was studied by transmission digital microscopy and western blot. Lipid metabolism was investigated by staining of lipid droplets (LDs) with BODIPY 493/503.
Outcomes: We discovered that the proliferative and migratory capacities of the cells had been vastly lowered by glycation, which might be defined by a rise in fibroblast tensile energy. Measurement of the mobile vitality steadiness didn’t point out that there was a change within the price of oxygen consumption of the fibroblasts. Evaluation of collagen I revealed that glyoxal didn’t affect kind I collagen secretion though it did disrupt collagen I maturation and it prevented its deposition within the extracellular matrix. We famous a pronounced enhance within the variety of LDs after glyoxal therapy. AMPK phosphorylation was lowered by glyoxal therapy but it surely was not accountable for the buildup of LDs.
Conclusion: Glyoxal promotes a change in fibroblast conduct in favor of lipogenic exercise that might be concerned in delaying wound therapeutic.
) Fibroblasts/Epithelial Cells Antibody (RPE) |
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| abx413037-100tests | Abbexa | 100 tests | EUR 676 |
Fibroblasts/Epithelial Cells Antibody (RPE) |
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| abx413038-25tests | Abbexa | 25 tests | EUR 356 |
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| RPE001 | Neuromics | 500,000 Cells | EUR 1288 |
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| T0572 | ABM | 1x106 cells / 1.0 ml | EUR 746 |
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| T0600 | ABM | 1x106 cells / 1.0 ml | EUR 630 |
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| 4-20261 | CHI Scientific | ea | Ask for price |
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| T0360 | ABM | 1x106 cells / 1.0 ml | Ask for price |
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| T0486 | ABM | 1x106 cells / 1.0 ml | EUR 1036 |
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| SC00A1-PTEC | Neuromics | 500,000 Cells | EUR 1321 |
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| SC00A5 | Neuromics | 500,000 Cells | EUR 905 |
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| T0454 | ABM | 1x106 cells / 1.0 ml | EUR 1036 |
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| T0485 | ABM | 1x106 cells / 1.0 ml | EUR 1036 |
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| 2-96075 | CHI Scientific | 1 Kit | Ask for price |
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| 2-96094 | CHI Scientific | 1 Kit | Ask for price |
 Human Prostate PrimaCell: Normal Prostate Epithelial Cells |
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| 2-96099 | CHI Scientific | 1 Kit | Ask for price |
 Human Ureter PrimaCell2: Normal Ureter Epithelial Cells |
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| 2-96112 | CHI Scientific | 1 Kit | Ask for price |
 Human Urethral PrimaCell: Normal Urethral Epithelial Cells |
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| 2-96113 | CHI Scientific | 1 Kit | Ask for price |
 Human Colon PrimaCell: Normal Colorectal Epithelial Cells |
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| 2-96115 | CHI Scientific | 1 Kit | Ask for price |
 Human Pancreas PrimaCell 2: Pancreatic Epithelial Cells |
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| 2-96123 | CHI Scientific | 1 Kit | Ask for price |
 - SV40) Immortalized Human Mammary Epithelial Cells (HMEC 2.6) - SV40 |
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| T0455 | ABM | 1x106 cells / 1.0 ml | EUR 1036 |
) Immortalized Mouse Small Intestinal Epithelial Cells-Conditionally (MSIE) |
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| T0568 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Human Tonsillar Epithelial Cells (E6/E7 HTE) |
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| T0660 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Mouse Prolactin-Responsive Mammary Epithelial Cells (HC11) |
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| T0672 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Human Cystic Fibrosis Tracheobronchial Epithelial Cells (CFT1) |
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| T0681 | ABM | 1x106 cells / 1.0 ml | EUR 572 |
 Mouse Breast PrimaCell: Normal Mammary Epithelial Primary Cells |
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| 2-82021 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Eye PrimaCell5: Normal Retinal Pigment Epithelial Cells |
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 Mouse Intestine PrimaCell3: Normal Intestinal Mucosa Epithelial Cells |
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 Mouse Kidney PrimaCell8: Normal Renal Tubular Epithelial Cells |
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| 2-82063 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells |
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| 2-82088 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Lung PrimaCell 7: Alveolar Epithelial Cells II |
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| 2-82101 | CHI Scientific | 1 Kit | Ask for price |
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 Rat Lung PrimaCell 7: Alveolar Epithelial Cells II |
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 Human Breast PrimaCell: Normal Mammary Epithelial Primary Cells |
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| 2-96104 | CHI Scientific | 1 Kit | Ask for price |
 Human Lung PrimaCell 7: Alveolar Epithelial Cells II |
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| 2-96122 | CHI Scientific | 1 Kit | Ask for price |
 TIMP-2, human fibroblasts |
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| 7788-5 | Biovision | EUR 338 | |
 Immortalized Human Cardiac Fibroblasts |
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| T0446 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Human Uterine Fibroblasts |
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| T0610 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 FBS, Fibroblasts Optimized I |
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| F0691-050 | GenDepot | 500ml | Ask for price |
 Human Fibroblasts-GFP Expressing |
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| GFP07 | Neuromics | 500,000 Cells in T25 flask | EUR 1354 |
 Cells - hTERT) Immortalized Human Mammary Epithelial Progenitor (K5+/K19+) Cells - hTERT |
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| T0452 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Mouse Retinal Pigmented Epithelial Cells - HPV16 E6/E7 |
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| T0574 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Human Endocervical Epithelial Cells- HPV E6/E7 (A2EN) |
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| T0595 | ABM | 1x106 cells / 1.0 ml | EUR 688 |
 Rat Thyroid Tissue Preparation Buffer: Normal Thyroid Epithelial Cells |
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| 9-80325 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Airway PrimaCell1: Normal Bronchial and Tracheal Epithelial Cells |
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| 2-82001 | CHI Scientific | 1 Kit | Ask for price |
 Rat Airway PrimaCell1: Normal Bronchial and Tracheal Epithelial Cells |
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| 2-82501 | CHI Scientific | 1 Kit | Ask for price |
 Human Airway PrimaCell2: Normal Bronchial and Tracheal Epithelial Cells |
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| 2-96002 | CHI Scientific | 1 Kit | Ask for price |
 Rat Bladder PrimaCell1: Normal Bladder Epithelial Cells Growth Medium |
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| 9-25006 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Cervix PrimaCell1: Normal Cervical Epithelial Cells Growth Medium |
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| 9-25024 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Cervix PrimaCell4: Normal Endometrial Epithelial Cells Growth Medium |
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| 9-25027 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Colon PrimaCell1: Normal Colorectal Epithelial Cells Growth Medium |
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| 9-25029 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Esophagus PrimaCell1: Normal Esophageal Epithelial Cells Growth Medium |
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| 9-25036 | CHI Scientific | 5 x 100 ml | Ask for price |
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| 9-25039 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Eye PrimaCell4: Normal Lens Epithelial Cells Growth Medium |
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| 9-25041 | CHI Scientific | 5 x 100 ml | Ask for price |
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| 9-25056 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Ovary PrimaCell1: Normal Ovarian Epithelial Cells Growth Medium |
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| 9-25076 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Prostate PrimaCell: Normal Prostate Epithelial Cells Growth Medium |
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| 9-25080 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Ureter PrimaCell: Normal Ureter Epithelial Cells Growth Medium |
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| 9-25088 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Urethral PrimaCell: Normal Urethral Epithelial Cells Growth Medium |
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| 9-25089 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Thyroid PrimaCell: Normal Thyroid Epithelial Cells Growth Medium |
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| 9-25098 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Bladder PrimaCell1: Normal Bladder Epithelial Cells Growth Medium |
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| 9-32006 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Cervix PrimaCell1: Normal Cervical Epithelial Cells Growth Medium |
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| 9-32023 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Cervix PrimaCell4: Normal Endometrial Epithelial Cells Growth Medium |
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| 9-32026 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Colon PrimaCell: Normal Colorectal Epithelial Cells Growth Medium |
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| 9-32028 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Esophagus PrimaCell1: Normal Esophageal Epithelial Cells Growth Medium |
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| 9-32035 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Eye PrimaCell2: Normal Corneal Epithelial Cells Growth Medium |
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| 9-32038 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Eye PrimaCell4: Normal Lens Epithelial Cells Growth Medium |
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| 9-32040 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Kidney PrimaCell2: Normal Kidney Epithelial Cells Growth Medium |
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| 9-32057 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Ovary PrimaCell1: Normal Ovarian Epithelial Cells Growth Medium |
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| 9-32077 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Prostate PrimaCell: Normal Prostate Epithelial Cells Growth Medium |
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| 9-32083 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Ureter PrimaCell: Normal Ureter Epithelial Cells Growth Medium |
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| 9-32092 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Urethral PrimaCell: Normal Urethral Epithelial Cells Growth Medium |
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| 9-32093 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Thyroid PrimaCell: Normal Thyroid Epithelial Cells Growth Medium |
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| 9-32103 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Airway PrimaCell1: Normal Airway Epithelial Cells Growth Medium |
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| 9-46001 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Bladder PrimaCell1: Normal Bladder Epithelial Cells Growth Medium |
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| 9-46007 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Cervix PrimaCell1: Normal Cervical Epithelial Cells Growth Medium |
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| 9-46044 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Cervix PrimaCell4: Normal Endometrial Epithelial Cells Growth Medium |
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| 9-46047 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Esophagus PrimaCell1: Normal Esophageal Epithelial Cells Growth Medium |
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| 9-46055 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Eye PrimaCell2: Normal Corneal Epithelial Cells Growth Medium |
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| 9-46058 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Eye PrimaCell4: Normal Lens Epithelial Cells Growth Medium |
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| 9-46060 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Kidney PrimaCell2: Normal Kidney Epithelial Cells Growth Medium |
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| 9-46075 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Ovary PrimaCell1: Normal Ovarian Epithelial Cells Growth Medium |
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| 9-46094 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Prostate PrimaCell: Normal Prostate Epithelial Cells Growth Medium |
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| 9-46099 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Ureter PrimaCell2: Normal Ureter Epithelial Cells Growth Medium |
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| 9-46112 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Urethral PrimaCell: Normal Urethral Epithelial Cells Growth Medium |
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| 9-46113 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Colon PrimaCell: Normal Colorectal Epithelial Cells Growth Medium |
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| 9-46115 | CHI Scientific | 5 x 100 ml | Ask for price |
L’agoniste CD40 ciblé sur la protéine α d’activation des fibroblastes se synergise avec la radiothérapie dans les tumeurs murines de la tête et du cou HPV-positives
Goal: The incidence of human papillomavirus-associated head and neck squamous cell carcinoma (HPV+-HNSCC) is rising worldwide and though present therapeutic modalities are environment friendly within the majority of sufferers, there’s a excessive price of therapy failures. Thus, novel mixture approaches are urgently wanted to attain higher illness management in sufferers with HPV+-HNSCC. We investigated the security and therapeutic efficacy of a novel fibroblast activation protein (FAP)-targeted CD40 agonist (FAP-CD40) together with native hypofractionated radiation in a syngeneic HPV+-HNSCC mannequin.
Experimental design: Utilizing an established orthotopic mannequin, we handled tumor-bearing mice with native hypofractionated radiotherapy (2 × 6 Gy) alone or together with a systemic administration of the FAP-CD40 antibody. Following up the mice, we evaluated the adjustments within the tumor microenvironment (TME) by immunofluorescence, FACS, and NanoString RNA evaluation.
Outcomes: The suboptimal radiotherapy routine chosen failed to manage tumors within the handled mice. The FAP-CD40 administered in monotherapy transiently managed tumor development, whereas the mixed remedy induced sturdy full responses in additional than 80% of the tumor-bearing mice. This notable efficacy relied on the radiotherapy-induced transforming of the TME and activation of the CD8+ T-cell-cDC1 axis and was devoid of the systemic toxicity regularly related to CD40-targeted remedy. Furthermore, the strong immunologic reminiscence developed successfully prevented tumor relapses, a typical function in sufferers with HNSCC.
Conclusions: Our examine offers proof of idea, in addition to mechanistic insights of the therapeutic efficacy of a bispecific FAP-CD40 mixed with native radiotherapy in a FAP+-HNSCC mannequin rising general survival and inducing long-term antitumor immunity.
a restriction tumorale par le collagène de kind I s’oppose aux effets de promotion des tumeurs des fibroblastes associés au most cancers
Most cancers-associated fibroblasts (CAF) might exert tumor-promoting and tumor-suppressive features, however the mechanisms underlying these opposing results stay elusive. Right here, we sought to grasp these doubtlessly opposing features by interrogating purposeful relationships between CAF subtypes, their mediators, desmoplasia and tumor development in wide selection of tumor varieties metastasizing to the liver, the commonest organ website for metastasis.
Depletion of hepatic stellate cells (HSC), which represented primary supply of CAF in mice and sufferers in our examine, or depletion of all CAF decreased tumor development and mortality in desmoplastic colorectal and pancreatic metastasis, however not in non-desmoplastic metastatic tumors. Single cell RNA-sequencing together with CellPhoneDB ligand-receptor evaluation, in addition to research in immune cell-depleted and HSC-selective knockout mice uncovered direct CAF-tumor interactions as tumor-promoting mechanism, mediated by myofibroblastic CAF (myCAF)-secreted hyaluronan and inflammatory CAF (iCAF)-secreted HGF.
These results had been opposed by myCAF-expressed type-I collagen, which suppressed tumor development by mechanically restraining tumor unfold, overriding its personal stiffness-induced mechanosignals. In abstract, mechanical restriction by type-I collagen opposes the general tumor-promoting results of CAF, thus offering a mechanistic rationalization for his or her twin features in most cancers. Therapeutic focusing on of tumor-promoting CAF mediators whereas preserving type-I collagen might convert CAF from tumor-promoting to tumor-restricting.
Évaluation clinique, biométrique et échographique des effets de la greffe de fibroblastes autologues sur les rides du pli nasolabial
Background: Feeling stunning and staying younger have all the time been necessary to the individuals. Due to this fact, an in depth physique of analysis has centered on the efforts made to take away the pores and skin issues, particularly wrinkles. Fibroblast cells of the pores and skin are the assorted autologous cells at present utilized in repairing a number of wounds, scars, and pores and skin getting old. Thus, the current examine was carried out to evaluate the efficacy of the transplantation of the fibroblast cells in eliminating the facial wrinkles utilizing the biometric evaluation and to optimize the utility of this system on this therapy.
Strategies: The current examine was carried out on 22 male and feminine sufferers aged between 35 – 60 years previous. Samples had been collected from the retro-auricular area, and the fibroblast cells had been remoted and cultured. Topics acquired three injections with autologous fibroblasts at 2-week intervals. The sufferers had been adopted up for six months and structural adjustments of their wrinkles had been assessed by the sonography in addition to the VisioFace software program, cutometer, tewameter, and colorimeter.
Outcomes: The outcomes obtained utilizing the VisioFace software program confirmed the numerous phenotypic adjustments within the sufferers after the nasolabial injections (81.42±23.97 vs. 60.91±21.91, P=0.0001). The outcomes confirmed a major enhance within the complete pores and skin density (13.73±6.30 vs. 26.27±7.93, P=0.0001), dermis density (11.28±5.21 vs. 31.88±7.96, P=0.0001), dermis density (27.68±23.15 vs. 49.21±45.68, P=0.046), and dermis thickness (798.09±133.51 μm vs. 905.59±240.67 μm, P=0.036) in comparison with pre-treatment.
Conclusion: The findings of the examine revealed that the injection of autologous fibroblasts could be efficient in restoring the getting old pores and skin, particularly within the nasolabial area, and can be utilized as a secure rejuvenating technique.
Immortalized Human Cardiac Fibroblasts |
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| T0446 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Uterine Fibroblasts |
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| T0610 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Human Fibroblasts-GFP Expressing |
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| GFP07 | Neuromics | 500,000 Cells in T25 flask | EUR 1354 |
 Fibroblasts/Epithelial Cells Antibody |
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| abx413035-02mg | Abbexa | 0.2 mg | EUR 648 |
Fibroblasts/Epithelial Cells Antibody |
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| abx413036-25ug | Abbexa | 25 ug | EUR 300 |
 Immortalized Human Gingival Fibroblasts- hTERT |
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| T0026 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Human Mammary Fibroblasts (HMF3A) |
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| T0153 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Human Mammary Fibroblasts (HMF3S) |
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| T0154 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Human Neonatal Fibroblasts - hTERT |
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| T0344 | ABM | 1x106 cells / 1.0 ml | Ask for price |
Immortalized Human Pulmonary Fibroblasts Cells |
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| T0490 | ABM | 1x106 cells / 1.0 ml | Ask for price |
) Immortalized Human Corneal Fibroblasts (IHCF) |
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| T0578 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Human Diploid Fibroblasts - hTERT |
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| T1013 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Human Cancer PrimaCell7: Esophageal Fibroblasts |
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| 2-96030 | CHI Scientific | 1 Kit | Ask for price |
Fibroblasts/Epithelial Cells Antibody (RPE) |
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| abx413037-100tests | Abbexa | 100 tests | EUR 676 |
Fibroblasts/Epithelial Cells Antibody (RPE) |
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| abx413038-25tests | Abbexa | 25 tests | EUR 356 |
FBS, Fibroblasts Optimized I |
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| F0691-050 | GenDepot | 500ml | Ask for price |
 Human Bladder PrimaCell2: Normal Bladder Fibroblasts |
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| 2-96008 | CHI Scientific | 1 Kit | Ask for price |
 Human Brain PrimaCell1: Normal Brain Fibroblasts |
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| 2-96013 | CHI Scientific | 1 Kit | Ask for price |
 Human Cervix PrimaCell2: Normal Cervical Fibroblasts |
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| 2-96045 | CHI Scientific | 1 Kit | Ask for price |
 Human Eye PrimaCell3: Normal Corneal Fibroblasts |
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| 2-96059 | CHI Scientific | 1 Kit | Ask for price |
 Human Heart PrimaCell3: Normal Heart Fibroblasts |
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| 2-96068 | CHI Scientific | 1 Kit | Ask for price |
 Human Lung PrimaCell1: Normal Lung Fibroblasts |
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| 2-96081 | CHI Scientific | 1 Kit | Ask for price |
 Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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| 2-96089 | CHI Scientific | 1 Kit | Ask for price |
 Human Mouth PrimaCell: Normal Periodontal Fibroblasts |
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| 2-96090 | CHI Scientific | 1 Kit | Ask for price |
 Human Skin PrimaCell: Normal Skin Fibroblasts |
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| 2-96103 | CHI Scientific | 1 Kit | Ask for price |
) Immortalized Rat Embryonic Fibroblasts (18IM) |
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| T0354 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Medium |
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| 9-46030 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts |
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| 2-96051 | CHI Scientific | 1 Kit | Ask for price |
 Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts |
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| 2-96083 | CHI Scientific | 1 Kit | Ask for price |
Mouse Anti Human Fibroblasts/Epithelial Cells Monoclonal Antibody,RPE |
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| DMABT-49595MH | Creative Diagnostics | 25 TEST | EUR 429 |
 Human Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium |
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| 9-46008 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium |
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| 9-46013 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium |
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| 9-46045 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium |
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| 9-46059 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium |
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| 9-46068 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Lung PrimaCell1: Normal Lung Fibroblasts Growth Medium |
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| 9-46081 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium |
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| 9-46089 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Mouth PrimaCell: Normal Periodontal Fibroblasts Growth Medium |
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| 9-46090 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Skin PrimaCell: Normal Skin Fibroblasts Growth Medium |
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| 9-46103 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Cancer Tissue Preparation Buffer 7: Esophageal Fibroblasts |
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| 9-80030 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Mouth Tissue Preparation Buffer: Normal Periodontal Fibroblasts |
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| 9-80090 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts |
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| 2-82007 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Brain PrimaCell1: Normal Brain Fibroblasts |
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| 2-82010 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts |
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| 2-82024 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Eye PrimaCell3: Normal Corneal Fibroblasts |
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| 2-82039 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Heart PrimaCell3: Normal Heart Fibroblasts |
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| 2-82047 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Lung PrimaCell2: Normal Lung Fibroblasts |
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| 2-82065 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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| 2-82073 | CHI Scientific | 1 Kit | Ask for price |
 Rat Bladder PrimaCell2: Normal Bladder Fibroblasts |
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| 2-82507 | CHI Scientific | 1 Kit | Ask for price |
 Rat Brain PrimaCell1: Normal Brain Fibroblasts |
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| 2-82511 | CHI Scientific | 1 Kit | Ask for price |
 Rat Cervix PrimaCell2: Normal Cervical Fibroblasts |
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| 2-82525 | CHI Scientific | 1 Kit | Ask for price |
 Rat Eye PrimaCell3: Normal Corneal Fibroblasts |
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| 2-82540 | CHI Scientific | 1 Kit | Ask for price |
 Rat Heart PrimaCell3: Normal Heart Fibroblasts |
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| 2-82548 | CHI Scientific | 1 Kit | Ask for price |
 Rat Lung PrimaCell1: Normal Lung Fibroblasts |
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| 2-82564 | CHI Scientific | 1 Kit | Ask for price |
 Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts |
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| 2-82572 | CHI Scientific | 1 Kit | Ask for price |
 Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium |
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| 9-46051 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Medium |
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| 9-46083 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts |
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| 9-80008 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts |
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| 9-80013 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts |
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| 9-80045 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts |
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| 9-80059 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts |
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| 9-80068 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Lung Tissue Preparation Buffer 1: Normal Lung Fibroblasts |
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| 9-80081 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts |
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| 9-80089 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Skin Tissue Preparation Buffer 3: Normal Skin Fibroblasts |
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| 9-80103 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts |
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| 2-96004 | CHI Scientific | 1 Kit | Ask for price |
 Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-Myc |
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| T0253 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-SV40 |
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| T0257 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-Ras |
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| T0258 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Immortalized Bcl-x Mouse Embryonic Fibroblasts - SV40T |
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| T0749 | ABM | 1x106 cells / 1.0 ml | Ask for price |
 Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts |
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| 2-82031 | CHI Scientific | 1 Kit | Ask for price |
 Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts |
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| 2-82067 | CHI Scientific | 1 Kit | Ask for price |
 Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts |
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| 2-82532 | CHI Scientific | 1 Kit | Ask for price |
 Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts |
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| 2-82566 | CHI Scientific | 1 Kit | Ask for price |
 Human Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts |
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| 9-80051 | CHI Scientific | 1 x 100 ml | Ask for price |
 Human Lung Tissue Preparation Buffer 3: Normal Pulmonary Artery Fibroblasts |
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| 9-80083 | CHI Scientific | 1 x 100 ml | Ask for price |
, Mouse and Rat) Kidney Dissociation System 5 (Fibroblasts), Mouse and Rat |
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| 4-29295 | CHI Scientific | ea | Ask for price |
 Rat Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium |
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| 9-25007 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium |
|||
| 9-25011 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium |
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| 9-25025 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium |
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| 9-25040 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium |
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| 9-25048 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Lung PrimaCell1: Normal Lung Fibroblasts Growth Medium |
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| 9-25064 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium |
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| 9-25072 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium |
|||
| 9-32007 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium |
|||
| 9-32010 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium |
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| 9-32024 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium |
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| 9-32039 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium |
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| 9-32047 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Lung PrimaCell2: Normal Lung Fibroblasts Growth Medium |
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| 9-32065 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium |
|||
| 9-32073 | CHI Scientific | 5 x 100 ml | Ask for price |
 Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts Growth Medium |
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| 9-46004 | CHI Scientific | 5 x 100 ml | Ask for price |
, Mouse and Rat) Heart Dissociation System 11 (Cardiomycytes,Fibroblasts), Mouse and Rat |
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| 4-20281 | CHI Scientific | ea | Ask for price |
 Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium |
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| 9-25032 | CHI Scientific | 5 x 100 ml | Ask for price |
 Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Medium |
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| 9-25066 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium |
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| 9-32031 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts Growth Medium |
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| 9-32067 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts |
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| 9-80121 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts |
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| 9-80124 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts |
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| 9-80138 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts |
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| 9-80153 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts |
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| 9-80161 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Lung Tissue Preparation Buffer 2: Normal Lung Fibroblasts |
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| 9-80179 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts |
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| 9-80187 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts |
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| 9-80214 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts |
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| 9-80218 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts |
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| 9-80232 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts |
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| 9-80247 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts |
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| 9-80255 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Lung Tissue Preparation Buffer 1: Normal Lung Fibroblasts |
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| 9-80271 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts |
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| 9-80279 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts |
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| 2-82003 | CHI Scientific | 1 Kit | Ask for price |
 Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts |
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| 2-82503 | CHI Scientific | 1 Kit | Ask for price |
 Human Airway Tissue Preparation Buffer 4: Normal Bronchial and and Tracheal Fibroblasts |
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| 9-80004 | CHI Scientific | 1 x 100 ml | Ask for price |
, Mouse and Rat) Lung Dissociation System 6 (Fibroblasts & Type II), Mouse and Rat |
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| 4-20316 | CHI Scientific | ea | Ask for price |
 Mouse Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts |
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| 9-80145 | CHI Scientific | 1 x 100 ml | Ask for price |
 Mouse Lung Tissue Preparation Buffer 4: Normal Pulmonary Artery Fibroblasts |
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| 9-80181 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts |
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| 9-80239 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Lung Tissue Preparation Buffer 3: Normal Pulmonary Artery Fibroblasts |
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| 9-80273 | CHI Scientific | 1 x 100 ml | Ask for price |
) Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47030 | CHI Scientific | 1 Set | Ask for price |
Cartilage Dissociation System 1 (Mesenchymal, Fibroblasts, Epithelial-like), Mouse and Rat |
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| 4-20231 | CHI Scientific | ea | Ask for price |
 Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Medium |
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| 9-25003 | CHI Scientific | 5 x 100 ml | Ask for price |
 Mouse Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Medium |
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| 9-32003 | CHI Scientific | 5 x 100 ml | Ask for price |
) Human Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47008 | CHI Scientific | 1 Set | Ask for price |
) Human Brain PrimaCell1: Normal Brain Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47013 | CHI Scientific | 1 Set | Ask for price |
) Human Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47045 | CHI Scientific | 1 Set | Ask for price |
) Human Eye PrimaCell3: Normal Corneal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47059 | CHI Scientific | 1 Set | Ask for price |
) Human Heart PrimaCell3: Normal Heart Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47068 | CHI Scientific | 1 Set | Ask for price |
) Human Lung PrimaCell1: Normal Lung Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47081 | CHI Scientific | 1 Set | Ask for price |
) Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47089 | CHI Scientific | 1 Set | Ask for price |
) Human Mouth PrimaCell: Normal Periodontal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47090 | CHI Scientific | 1 Set | Ask for price |
) Human Skin PrimaCell: Normal Skin Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47103 | CHI Scientific | 1 Set | Ask for price |
 Mouse Ariway Tissue Preparation Buffer 3: Normal Bronchial and and Tracheal Fibroblasts |
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| 9-80117 | CHI Scientific | 1 x 100 ml | Ask for price |
 Rat Ariway Tissue Preparation Buffer 3: Normal Bronchial and and Tracheal Fibroblasts |
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| 9-80210 | CHI Scientific | 1 x 100 ml | Ask for price |
) Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47051 | CHI Scientific | 1 Set | Ask for price |
) Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47083 | CHI Scientific | 1 Set | Ask for price |
) Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-47004 | CHI Scientific | 1 Set | Ask for price |
) Rat Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26007 | CHI Scientific | 1 Set | Ask for price |
) Rat Brain PrimaCell1: Normal Brain Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26011 | CHI Scientific | 1 Set | Ask for price |
) Rat Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26025 | CHI Scientific | 1 Set | Ask for price |
) Rat Eye PrimaCell3: Normal Corneal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26040 | CHI Scientific | 1 Set | Ask for price |
) Rat Heart PrimaCell3: Normal Heart Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26048 | CHI Scientific | 1 Set | Ask for price |
) Rat Lung PrimaCell1: Normal Lung Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26064 | CHI Scientific | 1 Set | Ask for price |
) Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-26072 | CHI Scientific | 1 Set | Ask for price |
) Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-33007 | CHI Scientific | 1 Set | Ask for price |
) Mouse Brain PrimaCell1: Normal Brain Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-33010 | CHI Scientific | 1 Set | Ask for price |
) Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-33024 | CHI Scientific | 1 Set | Ask for price |
) Mouse Eye PrimaCell3: Normal Corneal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
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| 9-33039 | CHI Scientific | 1 Set | Ask for price |
) Mouse Heart PrimaCell3: Normal Heart Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-33047 | CHI Scientific | 1 Set | Ask for price |
) Mouse Lung PrimaCell2: Normal Lung Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-33065 | CHI Scientific | 1 Set | Ask for price |
) Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-33073 | CHI Scientific | 1 Set | Ask for price |
) Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-26032 | CHI Scientific | 1 Set | Ask for price |
) Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-26066 | CHI Scientific | 1 Set | Ask for price |
) Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-33031 | CHI Scientific | 1 Set | Ask for price |
) Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-33067 | CHI Scientific | 1 Set | Ask for price |
) Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-26003 | CHI Scientific | 1 Set | Ask for price |
) Mouse Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Supplements with Serum (for 500 ml medium) |
|||
| 9-33003 | CHI Scientific | 1 Set | Ask for price |
 Human Albumin antibody |
|||
| 70R-7567 | Fitzgerald | 1 mg | EUR 140 |
|
Description: Affinity purified Goat polyclonal Human Albumin antibody |
|||
 human Splunc2 Antibody |
|||
| BF0019 | Affbiotech | 200ul | EUR 376 |
|
Description: human Splunc2 antibody detects endogenous levels of total human Splunc2. |
|||
 human Albumin Antibody |
|||
| BF0544 | Affbiotech | 200ul | EUR 376 |
|
Description: human Albumin antibody detects endogenous levels of total human Albumin. |
|||
 Human P16 Antibody |
|||
| BF0580 | Affbiotech | 200ul | EUR 376 |
|
Description: Human P16 antibody detects endogenous levels of total Human P16. |
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Human Albumin antibody |
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| 20C-CR2116R | Fitzgerald | 1 ml | EUR 260 |
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Description: Rabbit polyclonal Human Albumin antibody |
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 Human RBC antibody |
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| 20R-RR003 | Fitzgerald | 5 mg | EUR 554 |
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Description: Rabbit polyclonal Human RBC antibody |
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Human RBC antibody |
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| 20R-RR006 | Fitzgerald | 20 mg | EUR 327 |
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Description: Rabbit polyclonal Human RBC antibody |
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Human Albumin antibody |
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| 70C-CR2116GAP | Fitzgerald | 1 mg | EUR 208 |
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Description: Affinity purified Goat polyclonal Human Albumin antibody |
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 Antibody) DPPIV (Human) Antibody |
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| 6693-50 | Biovision | EUR 457 | |
 Human Macrophage antibody |
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| 10R-M102a | Fitzgerald | 200 ug | EUR 575 |
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Description: Mouse monoclonal Macrophage L1 protein Calprotectin antibody |
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 Human TFPI Antibody |
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| 10-2815 | Fitzgerald | 500 ug | EUR 727 |
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Description: Mouse anti-Human TFPI Antibody |
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 Human IgM antibody |
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| 10-3149 | Fitzgerald | 1 mg | EUR 219 |
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Description: Mouse Monoclonal Human IgM antibody |
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 Human IgG antibody |
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| 10-3150 | Fitzgerald | 1 mg | EUR 208 |
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Description: Mouse Monoclonal Human IgG antibody |
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 Human IgA antibody |
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| 10-3151 | Fitzgerald | 1 mg | EUR 219 |
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Description: Mouse Monoclonal Human IgA antibody |
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 Human IgE antibody |
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| 10-3152 | Fitzgerald | 1 mg | EUR 219 |
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Description: Mouse Monoclonal Human IgE antibody |
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Human Albumin antibody |
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| 20-S0103GND1-D0 | Fitzgerald | 10 ml | EUR 116 |
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Description: Goat polyclonal Human Albumin antibody |
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 Human Nuclei antibody |
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| 10R-8371 | Fitzgerald | 100 ul | EUR 457 |
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Description: Mouse monoclonal Human Nuclei antibody |
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Human IgG antibody |
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| 10R-8446 | Fitzgerald | 100 ul | EUR 393 |
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Description: Mouse monoclonal Human IgG antibody |
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